ZFIN is now using GRCz12tu for Genomic Data
Gene
dlk2
- ID
- ZDB-GENE-081107-4
- Name
- delta-like 2 homolog (Drosophila)
- Symbol
- dlk2 Nomenclature History
- Previous Names
-
- si:ch211-117c8.3
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable Notch binding activity. Acts upstream of or within negative regulation of Notch signaling pathway and negative regulation of angiogenesis. Predicted to be located in membrane. Orthologous to human DLK2 (delta like non-canonical Notch ligand 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from RodrÃguez et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR013032 | EGF-like, conserved site |
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Family | IPR050906 | Notch signaling pathway |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like, conserved site | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Notch signaling pathway |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B7S7 | InterPro | 373 | ||||||
| UniProtKB:A0A8M9PYA6 | InterPro | 378 | ||||||
| UniProtKB:A0A8M3B4Z9 | InterPro | 372 | ||||||
| UniProtKB:A0AC58H3S0 | InterPro | 372 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers