Gene

porcn

ID
ZDB-GENE-081105-87
Name
porcupine O-acyltransferase
Symbol
porcn Nomenclature History
Previous Names
  • porcn1 (1)
  • si:ch211-216k22.9
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to enable Wnt-protein binding activity and palmitoleoyltransferase activity. Acts upstream of or within Wnt protein secretion; convergent extension involved in gastrulation; and protein lipidation. Predicted to be active in endoplasmic reticulum and membrane. Is expressed in diencephalon; hindbrain; neural tube; spinal cord neural tube; and telencephalon. Human ortholog(s) of this gene implicated in focal dermal hypoplasia. Orthologous to human PORCN (porcupine O-acyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Chen et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Chen et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With porcn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
focal dermal hypoplasia Alliance Focal dermal hypoplasia 305600
Associated With porcn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004299 Membrane bound O-acyl transferase, MBOAT
Domain Details Per Protein
Protein Length Membrane bound O-acyl transferase, MBOAT
UniProtKB:A0A286Y8W9 443
UniProtKB:B0S7W7 442
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations