ZFIN is now using GRCz12tu for Genomic Data
Gene
prickle3
- ID
- ZDB-GENE-081105-86
- Name
- prickle homolog 3
- Symbol
- prickle3 Nomenclature History
- Previous Names
-
- si:ch211-194e1.5
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable zinc ion binding activity. Predicted to be active in mitochondrion and plasma membrane. Is expressed in corpuscles of Stannius. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy. Orthologous to human PRICKLE3 (prickle planar cell polarity protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Klingbeil et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Leber hereditary optic neuropathy, modifier of} | 308905 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | LIM1 prickle | LIM2 prickle | LIM3 prickle | PET domain | PET prickle | Prickle/Espinas/Testin | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8N7TE34 | InterPro | 783 | |||||||
| UniProtKB:A0A8M2BEN2 | InterPro | 717 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prickle3-202
(1)
|
Ensembl | 1,212 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers