Gene
si:dkey-32e23.4
- ID
- ZDB-GENE-081105-41
- Name
- si:dkey-32e23.4
- Symbol
- si:dkey-32e23.4 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have GTPase activity and microtubule binding activity. Predicted to be involved in several processes, including intracellular distribution of mitochondria; mitochondrial fragmentation involved in apoptotic process; and regulation of autophagy of mitochondrion. Predicted to localize to cytoplasm and membrane. Human ortholog(s) of this gene implicated in encephalopathy due to defective mitochondrial and peroxisomal fission 1 and optic atrophy 5. Orthologous to human DNM1L (dynamin 1 like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019762 | Dynamin, GTPase region, conserved site |
| Domain | IPR000375 | Dynamin stalk domain |
| Domain | IPR001401 | Dynamin, GTPase domain |
| Domain | IPR003130 | Dynamin GTPase effector |
| Domain | IPR020850 | GTPase effector domain |
| Domain | IPR030381 | Dynamin-type guanine nucleotide-binding (G) domain |
| Domain | IPR045063 | Dynamin, N-terminal |
| Family | IPR022812 | Dynamin |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | Dynamin | Dynamin, GTPase domain | Dynamin GTPase effector | Dynamin, GTPase region, conserved site | Dynamin, N-terminal | Dynamin stalk domain | Dynamin-type guanine nucleotide-binding (G) domain | GTPase effector domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BEQ1
|
658 | |||||||||
|
UniProtKB:F6P2T1
|
671 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-32e23.4-202
(1)
|
Ensembl | 3,060 nt | ||
| mRNA |
si:dkey-32e23.4-203
(1)
|
Ensembl | 2,016 nt | ||
| ncRNA |
si:dkey-32e23.4-002
(1)
|
Ensembl | 515 nt |
Interactions and Pathways
No data available
Plasmids
No data available