ZFIN is now using GRCz12tu for Genomic Data
Gene
rapgef1a
- ID
- ZDB-GENE-081105-26
- Name
- Rap guanine nucleotide exchange factor (GEF) 1a
- Symbol
- rapgef1a Nomenclature History
- Previous Names
-
- si:ch211-127h20.2
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within axonogenesis; somitogenesis; and vasculogenesis. Predicted to be active in plasma membrane. Orthologous to human RAPGEF1 (Rap guanine nucleotide exchange factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Li et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019804 | Ras guanine-nucleotide exchange factor, conserved site |
| Domain | IPR000651 | Ras-like guanine nucleotide exchange factor, N-terminal |
| Domain | IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain |
| Family | IPR008937 | Ras-like guanine nucleotide exchange factor |
| Homologous_superfamily | IPR023578 | Ras guanine nucleotide exchange factor domain superfamily |
| Homologous_superfamily | IPR036964 | Ras guanine-nucleotide exchange factor, catalytic domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Ras guanine-nucleotide exchange factor, conserved site | Ras guanine nucleotide exchange factor domain superfamily | Ras guanine-nucleotide exchange factors catalytic domain | Ras-like guanine nucleotide exchange factor | Ras-like guanine nucleotide exchange factor, N-terminal |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AUZ3 | InterPro | 999 | ||||||
| UniProtKB:A0A8M2BED2 | InterPro | 1085 | ||||||
| UniProtKB:A0A8M3B1T6 | InterPro | 1030 | ||||||
| UniProtKB:A0A8M3B4Q5 | InterPro | 1054 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rapgef1a-201
(1)
|
Ensembl | 3,081 nt | ||
| mRNA |
rapgef1a-202
(1)
|
Ensembl | 3,399 nt | ||
| mRNA |
rapgef1a-203
(1)
|
Ensembl | 2,907 nt | ||
| mRNA |
rapgef1a-204
(1)
|
Ensembl | 2,817 nt | ||
| mRNA |
rapgef1a-205
(1)
|
Ensembl | 3,039 nt | ||
| mRNA |
rapgef1a-206
(1)
|
Ensembl | 2,919 nt | ||
| mRNA |
rapgef1a-207
(1)
|
Ensembl | 2,910 nt | ||
| mRNA |
rapgef1a-208
(1)
|
Ensembl | 2,907 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers