Gene
soat1
- ID
- ZDB-GENE-081105-177
- Name
- sterol O-acyltransferase 1
- Symbol
- soat1 Nomenclature History
- Previous Names
-
- si:dkey-21p1.4
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable cholesterol O-acyltransferase activity; cholesterol binding activity; and fatty-acyl-CoA binding activity. Predicted to be involved in cholesterol efflux and cholesterol metabolic process. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including eye; hatching gland; pericardial region; pleuroperitoneal region; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Chagas disease. Orthologous to human SOAT1 (sterol O-acyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Chang et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Membrane bound O-acyl transferase, MBOAT | Sterol O-acyltransferase, ACAT/DAG/ARE types |
|---|---|---|---|---|
| UniProtKB:B0UYE4 | InterPro | 554 |
Interactions and Pathways
No data available
Plasmids
No data available