Gene

tgfbr2l

ID
ZDB-GENE-081105-143
Name
transforming growth factor beta receptor-like
Symbol
tgfbr2l Nomenclature History
Previous Names
  • si:dkey-101k6.5
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable several functions, including activin binding activity; transforming growth factor beta binding activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in several processes, including activin receptor signaling pathway; cellular response to growth factor stimulus; and heart development. Predicted to act upstream of or within several processes, including apoptotic process; cell surface receptor protein serine/threonine kinase signaling pathway; and protein phosphorylation. Predicted to be located in membrane raft. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa9311Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa41488Allele with one point mutationUnknownSplice SiteENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With tgfbr2l Human Ortholog
No data available
Associated With tgfbr2l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR015013 Transforming growth factor beta receptor 2 ectodomain
Family IPR000333 Ser/Thr protein kinase, TGFB receptor
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Domain Details Per Protein
Protein Additional Resources Length Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Ser/Thr protein kinase, TGFB receptor Snake toxin-like superfamily Transforming growth factor beta receptor 2 ectodomain Transforming growth factor-beta receptor, type II
UniProtKB:F1QAH4 InterPro 590
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 9
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:dkey-101k6.5-201 (1)
Ensembl
Ensembl 2,019 nt
ZFIN BLAST
mRNA si:dkey-101k6.5-202 (1)
Ensembl
Ensembl 1,551 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-101K6ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_683846 (1)
ZFIN BLASTNCBI BLASTMegaBLASTEnsemblUCSC BLAT
GenomicGenBank:BX255930 (1)185559 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:F1QAH4 (1)590 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
No data available
Citations
TSV
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