ZFIN is now using GRCz12tu for Genomic Data
Gene
tgfbr2l
- ID
- ZDB-GENE-081105-143
- Name
- transforming growth factor beta receptor-like
- Symbol
- tgfbr2l Nomenclature History
- Previous Names
-
- si:dkey-101k6.5
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including activin binding activity; transforming growth factor beta binding activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in several processes, including activin receptor signaling pathway; cellular response to growth factor stimulus; and heart development. Predicted to act upstream of or within several processes, including apoptotic process; cell surface receptor protein serine/threonine kinase signaling pathway; and protein phosphorylation. Predicted to be located in membrane raft. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR015013 | Transforming growth factor beta receptor 2 ectodomain |
| Family | IPR000333 | Ser/Thr protein kinase, TGFB receptor |
| Family | IPR017194 | Transforming growth factor-beta receptor, type II |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR045860 | Snake toxin-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Ser/Thr protein kinase, TGFB receptor | Snake toxin-like superfamily | Transforming growth factor beta receptor 2 ectodomain | Transforming growth factor-beta receptor, type II |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QAH4 | InterPro | 590 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-101k6.5-201
(1)
|
Ensembl | 2,019 nt | ||
| mRNA |
si:dkey-101k6.5-202
(1)
|
Ensembl | 1,551 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers