Gene
tgfbr2l
- ID
- ZDB-GENE-081105-143
- Name
- transforming growth factor beta receptor-like
- Symbol
- tgfbr2l Nomenclature History
- Previous Names
-
- si:dkey-101k6.5
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have several functions, including activin binding activity; transforming growth factor beta binding activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in heart development; protein phosphorylation; and transforming growth factor beta receptor signaling pathway. Predicted to localize to plasma membrane and receptor complex.
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
Binding_site | IPR017441 | Protein kinase, ATP binding site |
Domain | IPR000719 | Protein kinase domain |
Domain | IPR015013 | Transforming growth factor beta receptor 2 ectodomain |
Family | IPR000333 | Ser/Thr protein kinase, TGFB receptor |
Family | IPR017194 | Transforming growth factor-beta receptor, type II |
Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Homologous_superfamily | IPR045860 | Snake toxin-like superfamily |
Domain Details Per Protein
Protein | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Ser/Thr protein kinase, TGFB receptor | Snake toxin-like superfamily | Transforming growth factor beta receptor 2 ectodomain | Transforming growth factor-beta receptor, type II |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1QAH4
|
590 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
si:dkey-101k6.5-201
(1)
|
Ensembl | 2,019 nt | ||
mRNA |
si:dkey-101k6.5-202
(1)
|
Ensembl | 1,551 nt |
Interactions and Pathways
No data available
Plasmids
No data available