Gene
mtss1
- ID
- ZDB-GENE-081105-141
- Name
- MTSS I-BAR domain containing 1
- Symbol
- mtss1 Nomenclature History
- Previous Names
-
- si:dkey-46l15.1
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable actin binding activity and phospholipid binding activity. Predicted to be involved in cell projection assembly and membrane organization. Predicted to act upstream of or within plasma membrane organization. Predicted to be active in actin cytoskeleton and cytoplasmic side of plasma membrane. Orthologous to human MTSS1 (MTSS I-BAR domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| ct30bGt | Transgenic insertion | Unknown | Unknown | DNA | |
| la010952Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| la029247Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa11667 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa20817 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa20818 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa31543 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa33966 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa40790 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AH/BAR domain superfamily | I-BAR domain containing protein MTSS1/MTSS2 | IMD/I-BAR domain | WH2 domain |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B3P5 | InterPro | 743 | ||||
| UniProtKB:B0S6V2 | InterPro | 702 | ||||
| UniProtKB:A0A8M3B0S0 | InterPro | 734 | ||||
| UniProtKB:A0AB32TQT7 | InterPro | 743 | ||||
| UniProtKB:A0AB32TSI1 | InterPro | 693 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-242H13 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-46L15 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001123252 (1) | 2109 nt | ||
| Genomic | GenBank:BX530017 (1) | 164713 nt | ||
| Polypeptide | UniProtKB:A0A8M3B3P5 (1) | 743 aa |
- Cal, L., MegÍas, M., Cerdá-Reverter, J.M., Postlethwait, J.H., Braasch, I., Rotllant, J. (2017) BAC Recombineering of the Agouti Loci from Spotted Gar and Zebrafish Reveals the Evolutionary Ancestry of Dorsal-Ventral Pigment Asymmetry in Fish. Journal of experimental zoology. Part B, Molecular and developmental evolution. 328(7):697-708
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Trinh, A., Hochgreb, T., Graham, M., Wu, D., Ruf-Zamojski, F., Jayasena, C.S., Saxena, A., Hawk, R., Gonzalez-Serricchio, A., Dixson, A., Chow, E., Gonzales, C., Leung, H.Y., Solomon, I., Bronner-Fraser, M., Megason, S.G., and Fraser, S.E. (2011) A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Genes & Development. 25(21):2306-20
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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