Gene
dab2ipa
- ID
- ZDB-GENE-081104-516
- Name
- DAB2 interacting protein a
- Symbol
- dab2ipa Nomenclature History
- Previous Names
-
- si:dkey-83f4.1
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have GTPase activator activity. Predicted to be involved in several processes, including negative regulation of angiogenesis; negative regulation of vascular endothelial growth factor receptor signaling pathway; and reelin-mediated signaling pathway. Orthologous to human DAB2IP (DAB2 interacting protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhong et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR023152 | Ras GTPase-activating protein, conserved site |
| Domain | IPR000008 | C2 domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR001936 | Ras GTPase-activating domain |
| Domain | IPR021887 | Disabled homolog 2-interacting protein, C-terminal domain |
| Family | IPR039360 | Ras GTPase-activating protein |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
Domain Details Per Protein
| Protein | Length | C2 domain | C2 domain superfamily | Disabled homolog 2-interacting protein, C-terminal domain | PH-like domain superfamily | Pleckstrin homology domain | Ras GTPase-activating domain | Ras GTPase-activating protein | Ras GTPase-activating protein, conserved site | Rho GTPase activation protein |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B4Q7
|
1162 | |||||||||
|
UniProtKB:A0A8M3AUY3
|
1255 | |||||||||
|
UniProtKB:A0A8M3B1U1
|
1069 | |||||||||
|
UniProtKB:A0A8M6YZX5
|
1256 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dab2ipa-201
(1)
|
Ensembl | 3,414 nt | ||
| mRNA |
dab2ipa-203
(1)
|
Ensembl | 3,443 nt | ||
| ncRNA |
dab2ipa-002
(1)
|
Ensembl | 539 nt |
Interactions and Pathways
No data available
Plasmids
No data available