ZFIN is now using GRCz12tu for Genomic Data
Gene
lct
- ID
- ZDB-GENE-081104-434
- Name
- lactase
- Symbol
- lct Nomenclature History
- Previous Names
-
- si:dkey-79p17.2
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable beta-glucosidase activity and lactase activity. Predicted to be involved in cellobiose catabolic process and lactose catabolic process. Predicted to be active in external side of apical plasma membrane. Human ortholog(s) of this gene implicated in congenital lactase deficiency. Orthologous to human LCT (lactase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital lactase deficiency | Alliance | Lactase deficiency, congenital | 223000 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Glycoside hydrolase family 1 | Glycoside hydrolase family 1, active site | Glycoside hydrolase superfamily | Glycosyl hydrolases family 1, N-terminal conserved site |
|---|---|---|---|---|---|---|
| UniProtKB:A0AC58GHN5 | InterPro | 1803 | ||||
| UniProtKB:F1Q8B5 | InterPro | 1900 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers