Gene
tmem163a
- ID
- ZDB-GENE-081104-429
- Name
- transmembrane protein 163a
- Symbol
- tmem163a Nomenclature History
- Previous Names
-
- tmem163
- si:dkey-57b6.2
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable zinc ion binding activity. Acts upstream of or within myelination and oligodendrocyte development. Predicted to be located in bounding membrane of organelle and plasma membrane. Predicted to be active in synaptic vesicle membrane. Is expressed in Rohon-Beard neurons; brain; central nervous system; and spinal cord. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 25. Orthologous to human TMEM163 (transmembrane protein 163).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Yan et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypomyelinating leukodystrophy 25 | Alliance | Leukodystrophy, hypomyelinating, 25 | 620243 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cation efflux transmembrane domain superfamily | Transmembrane protein 163 |
|---|---|---|---|---|
| UniProtKB:B0UY98 | InterPro | 216 | ||
| UniProtKB:A0A8M2BF29 | InterPro | 285 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmem163a-201
(1)
|
Ensembl | 1,233 nt | ||
| mRNA |
tmem163a-202
(1)
|
Ensembl | 1,235 nt |
Interactions and Pathways
No data available
Plasmids
No data available