Gene
mcf2lb
- ID
- ZDB-GENE-081104-416
- Name
- mcf.2 cell line derived transforming sequence-like b
- Symbol
- mcf2lb Nomenclature History
- Previous Names
-
- sb:eu830
- si:dkey-46k9.10
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction. Is expressed in lateral line system; otic placode; and otic vesicle. Orthologous to human MCF2L (MCF.2 cell line derived transforming sequence like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu830 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Olson et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR001251 | CRAL-TRIO lipid binding domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Family | IPR051336 | Rho GTPase-activating Guanine Nucleotide Exchange Factors |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Repeat | IPR018159 | Spectrin/alpha-actinin |
Domain Details Per Protein
| Protein | Length | CRAL-TRIO lipid binding domain | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | PH-like domain superfamily | Pleckstrin homology domain | Rho GTPase-activating Guanine Nucleotide Exchange Factors | Spectrin/alpha-actinin |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8N7T881
|
1093 | ||||||||
|
UniProtKB:A0A8M9Q556
|
1088 | ||||||||
|
UniProtKB:A0A8M9Q336
|
1095 | ||||||||
|
UniProtKB:A0A8M9QBG1
|
1072 | ||||||||
|
UniProtKB:A0A8M9QK90
|
1097 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mcf2lb-201
(1)
|
Ensembl | 5,052 nt | ||
| mRNA |
mcf2lb-202
(1)
|
Ensembl | 1,543 nt | ||
| mRNA |
mcf2lb-203
(1)
|
Ensembl | 1,507 nt | ||
| mRNA |
mcf2lb-204
(1)
|
Ensembl | 5,025 nt | ||
| mRNA |
mcf2lb-205
(1)
|
Ensembl | 5,033 nt |
Interactions and Pathways
No data available
Plasmids
No data available