pidd1

ID

ZDB-GENE-081104-353

Name

p53-induced death domain protein 1

Symbol

pidd1 Nomenclature History

Previous Names

pidd
si:dkey-201c1.1

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to be involved in apoptotic process and intracellular signal transduction. Predicted to act upstream of or within DNA damage response and signal transduction. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 75. Orthologous to human PIDD1 (p53-induced death domain protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pidd1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal recessive intellectual developmental disorder 75	Alliance	Intellectual developmental disorder, autosomal recessive 75, with neuropsychiatric features and variant lissencephaly	619827

Associated With pidd1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000488	Death domain
Domain	IPR000906	ZU5 domain
Family	IPR019502	Peptidase S68, pidd
Family	IPR050216	Leucine-rich repeat domain-containing protein
Homologous_superfamily	IPR011029	Death-like domain superfamily
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype