Gene
lmod1a
- ID
- ZDB-GENE-081104-348
- Name
- leiomodin 1a (smooth muscle)
- Symbol
- lmod1a Nomenclature History
- Previous Names
-
- lmod1
- si:dkey-193l3.5
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have tropomyosin binding activity. Predicted to be involved in actin filament organization; muscle contraction; and myofibril assembly. Predicted to localize to striated muscle thin filament. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human LMOD1 (leiomodin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Megacystis-microcolon-intestinal hypoperistalsis syndrome 3 | 619362 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Leucine-rich repeat domain superfamily | Tropomodulin |
|---|---|---|---|
|
UniProtKB:A0A8M9PRG4
|
645 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lmod1a-201
(1)
|
Ensembl | 2,610 nt |
Interactions and Pathways
No data available
Plasmids
No data available