Gene

foxp3b

ID
ZDB-GENE-081104-332
Name
forkhead box P3b
Symbol
foxp3b Nomenclature History
Previous Names
  • si:dkey-16n15.5 (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity; metal ion binding activity; and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome and type 1 diabetes mellitus. Is expressed in head kidney. Orthologous to human FOXP3 (forkhead box P3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With foxp3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked 304790
Associated With foxp3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR030456 Fork head domain conserved site 2
Domain IPR001766 Fork head domain
Domain IPR032354 FOXP, coiled-coil domain
Domain IPR047413 Forkhead box protein P3, forkhead domain
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Forkhead box protein P3, forkhead domain Fork head domain Fork head domain conserved site 2 FOXP, coiled-coil domain Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A8M9PRD6 237
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA foxp3b-201 (1) Ensembl 2051 nt
mRNA foxp3b-202 (1) Havana 1131 nt
mRNA foxp3b-203 (1) Ensembl 2139 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations