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Gene

cxcl8a

ID
ZDB-GENE-081104-317
Name
chemokine (C-X-C motif) ligand 8a
Symbol
cxcl8a Nomenclature History
Previous Names
  • cxcl8
  • il8 (1)
  • cxcl-chr1a (1)
  • cxcl-chr1b (1)
  • CXCL8_L1_chr1 (1)
  • dr-chr1-CXCL8 (1)
  • si:dkey-151b16.2
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Enables chemokine activity. Acts upstream of or within several processes, including blood vessel morphogenesis; endothelial to hematopoietic transition; and leukocyte migration. Predicted to be located in extracellular space. Is expressed in several structures, including cardiovascular system; eye; integument; liver; and pleuroperitoneal region. Used to study vitamin D-dependent rickets. Human ortholog(s) of this gene implicated in bacterial gastritis; hepatocellular carcinoma; stomach carcinoma; and viral encephalitis. Orthologous to several human genes including CXCL8 (C-X-C motif chemokine ligand 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
70 figures from 48 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cxcl8a Human Ortholog
No data available
Associated With cxcl8a Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001811 Chemokine interleukin-8-like domain
Domain IPR033899 CXC Chemokine domain
Family IPR001089 CXC chemokine
Family IPR028469 Interleukin-8
Homologous_superfamily IPR036048 Chemokine interleukin-8-like superfamily
Domain Details Per Protein
Protein Length Chemokine interleukin-8-like domain Chemokine interleukin-8-like superfamily CXC chemokine CXC Chemokine domain Interleukin-8
UniProtKB:A0A0G2KYH9
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations