Gene
cxcl8a
- ID
- ZDB-GENE-081104-317
- Name
- chemokine (C-X-C motif) ligand 8a
- Symbol
- cxcl8a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Exhibits chemokine activity. Involved in several processes, including blood vessel morphogenesis; endothelial to hematopoietic transition; and leukocyte migration. Predicted to localize to extracellular space. Is expressed in several structures, including cardiovascular system; eye; integument; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to several human genes including CXCL8 (C-X-C motif chemokine ligand 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 74 figures from 51 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| vitamin D-dependent rickets | cxcl8auwm25/uwm25 | standard conditions | Cortes et al., 2016 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Chemokine interleukin-8-like domain | Chemokine interleukin-8-like superfamily | CXC chemokine | CXC Chemokine domain | Interleukin-8 |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A0G2KYH9
|
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available