Gene
dpp4
- ID
- ZDB-GENE-081104-277
- Name
- dipeptidyl-peptidase 4
- Symbol
- dpp4 Nomenclature History
- Previous Names
-
- si:ch73-2d23.3
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in anchoring junction and lamellipodium membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Middle East respiratory syndrome and type 2 diabetes mellitus. Orthologous to human DPP4 (dipeptidyl peptidase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR002471 | Peptidase S9, serine active site |
| Domain | IPR001375 | Peptidase S9, prolyl oligopeptidase, catalytic domain |
| Domain | IPR002469 | Dipeptidylpeptidase IV, N-terminal domain |
| Domain | IPR040522 | Dipeptidyl peptidase 4, low complexity region |
| Family | IPR050278 | Serine protease S9B/DPPIV |
| Homologous_superfamily | IPR029058 | Alpha/Beta hydrolase fold |
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Dipeptidyl peptidase 4, low complexity region | Dipeptidylpeptidase IV, N-terminal domain | Peptidase S9, prolyl oligopeptidase, catalytic domain | Peptidase S9, serine active site | Serine protease S9B/DPPIV |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B5DDZ4
|
742 |
Interactions and Pathways
No data available
Plasmids
No data available