Gene
steap3
- ID
- ZDB-GENE-081104-268
- Name
- STEAP family member 3, metalloreductase
- Symbol
- steap3 Nomenclature History
- Previous Names
-
- si:ch73-250a16.3
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have cupric reductase activity and ferric-chelate reductase (NADPH) activity. Predicted to be involved in copper ion import; iron ion import across cell outer membrane; and oxidation-reduction process. Predicted to localize to endosome and plasma membrane. Orthologous to human STEAP3 (STEAP3 metalloreductase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypochromic microcytic anemia | Alliance | ?Anemia, hypochromic microcytic, with iron overload 2 | 615234 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ferric reductase transmembrane component-like domain | NAD(P)-binding domain superfamily | Pyrroline-5-carboxylate reductase, catalytic, N-terminal | STEAP family metalloreductases |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M1RHF3
|
481 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
steap3-201
(1)
|
Ensembl | 2,155 nt |
Interactions and Pathways
No data available
Plasmids
No data available