Gene
steap3
- ID
- ZDB-GENE-081104-268
- Name
- STEAP family member 3, metalloreductase
- Symbol
- steap3 Nomenclature History
- Previous Names
-
- si:ch73-250a16.3
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable cupric reductase activity and ferric-chelate reductase (NADPH) activity. Predicted to be involved in copper ion import. Predicted to act upstream of or within iron ion homeostasis and monoatomic ion transport. Predicted to be located in endosome membrane. Predicted to be active in endosome and plasma membrane. Orthologous to human STEAP3 (STEAP3 metalloreductase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypochromic microcytic anemia | Alliance | ?Anemia, hypochromic microcytic, with iron overload 2 | 615234 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ferric reductase transmembrane component-like domain | NAD(P)-binding domain superfamily | Pyrroline-5-carboxylate reductase, catalytic, N-terminal | STEAP family metalloreductases |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M1RHF3
|
481 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
steap3-201
(1)
|
Ensembl | 2,155 nt |
Interactions and Pathways
No data available
Plasmids
No data available