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ZIRC
ZFIN ID: ZDB-GENE-081104-244
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Gene Name: coiled-coil domain containing 136b
Gene Symbol: ccdc136b    Nomenclature History

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Previous Name: si:ch73-146h23.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Ambiguous Mapping Details/Browsers
Description: Involved in negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification. Localizes to the cytoplasm. Is expressed in blastomere and notochord. Orthologous to human CCDC136 (coiled-coil domain containing 136).
Genome Resources: Alliance (1),  Gene:100321715 (1), 
GENE EXPRESSION
All Expression Data: Fig. 1 from Wei et al., 2016
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10942 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa26229 Point Mutation Unknown Splice Site ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ccdc136b N/A 1
    MO2-ccdc136b N/A 1
    PHENOTYPE
    Data: 3 figures from Wei et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH ccdc136b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ccdc136b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ccdc136b-201 (1)    Ensembl 2306
    Select Tool
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ccdc136b No data available
    MARKER RELATIONSHIPS
    ccdc136b Contained in: [BAC] CH73-146H23 (1) (order this), DKEY-22L11 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_002666937 (1) 3079 bp
    Select Tool
    Genomic GenBank:BX248111 (1) 185023 bp
    Select Tool
    Polypeptide UniProtKB:E9QD51 (1) 429 aa
    Select Tool
    Sequence Clusters UniGene:130463 (1)
    Sequence Information (all 15)
    ORTHOLOGY for ccdc136b ( Ambiguous )
    CITATIONS (11)