Gene
dynlt2b
- ID
- ZDB-GENE-081104-219
- Name
- dynein light chain Tctex-type 2B
- Symbol
- dynlt2b Nomenclature History
- Previous Names
-
- si:ch211-276k2.4 (1)
- tctex1d2
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in intraciliary retrograde transport. Predicted to be located in dynein axonemal particle. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in cytoplasm. Used to study ciliopathy. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Orthologous to human DYNLT2B (dynein light chain Tctex-type 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Schmidts et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Short-rib thoracic dysplasia 17 with or without polydactyly | 617405 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| ciliopathy | WT + MO1-dynlt2b + MO4-tp53 | standard conditions | Schmidts et al., 2015 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dynein light chain Tctex-1 like | Tctex-1-like superfamily |
|---|---|---|---|
|
UniProtKB:F1QMY1
|
150 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tctex1d2-201
(1)
|
Ensembl | 958 nt | ||
| mRNA |
tctex1d2-202
(1)
|
Ensembl | 489 nt |
Interactions and Pathways
No data available
Plasmids
No data available