ZFIN is now using GRCz12tu for Genomic Data
Gene

si:ch211-241b2.5

ID
ZDB-GENE-081104-192
Name
si:ch211-241b2.5
Symbol
si:ch211-241b2.5 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to be involved in several processes, including cell surface receptor signaling pathway; cellular response to lipopolysaccharide; and regulation of T cell activation. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in infantile onset multisystem autoimmune disease 5. Orthologous to several human genes including PDCD1LG2 (programmed cell death 1 ligand 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With si:ch211-241b2.5 Human Ortholog
No data available
Associated With si:ch211-241b2.5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003593 AAA+ ATPase domain
Domain IPR003599 Immunoglobulin domain subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR007111 NACHT nucleoside triphosphatase
Domain IPR013106 Immunoglobulin V-set domain
Family IPR051713 T-cell Activation and Immune Regulation Protein
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Additional Resources Length AAA+ ATPase domain Immunoglobulin domain subtype Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin V-set domain NACHT nucleoside triphosphatase P-loop containing nucleoside triphosphate hydrolase T-cell Activation and Immune Regulation Protein
UniProtKB:A0A8M3AL67 InterPro 760
UniProtKB:A0AB32TBY4 InterPro 555
UniProtKB:A0AB32TDG9 InterPro 527
UniProtKB:A0AB32TF72 InterPro 494
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:ch211-241b2.5-201 (1) Ensembl 1,396 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Citations