Gene
si:dkeyp-77c4.1
- ID
- ZDB-GENE-081103-36
- Name
- si:dkeyp-77c4.1
- Symbol
- si:dkeyp-77c4.1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in CINCA Syndrome; Muckle-Wells syndrome; autosomal dominant nonsyndromic deafness 34; familial cold autoinflammatory syndrome (multiple); and urticaria. Orthologous to several human genes including NLRP12 (NLR family pyrin domain containing 12); NLRP13 (NLR family pyrin domain containing 13); and NLRP14 (NLR family pyrin domain containing 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001870 | B30.2/SPRY domain |
| Domain | IPR003877 | SPRY domain |
| Domain | IPR003879 | Butyrophylin-like, SPRY domain |
| Domain | IPR006574 | SPRY-associated |
| Domain | IPR007111 | NACHT nucleoside triphosphatase |
| Domain | IPR029495 | NACHT-associated domain |
| Domain | IPR041075 | NOD1/2, winged helix domain |
| Domain | IPR041267 | NACHT, LRR and PYD domains-containing protein, helical domain HD2 |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Homologous_superfamily | IPR043136 | B30.2/SPRY domain superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
Domain Details Per Protein
| Protein | Length | B30.2/SPRY domain | B30.2/SPRY domain superfamily | Butyrophylin-like, SPRY domain | Concanavalin A-like lectin/glucanase domain superfamily | Leucine-rich repeat | Leucine-rich repeat domain superfamily | NACHT-associated domain | NACHT, LRR and PYD domains-containing protein, helical domain HD2 | NACHT nucleoside triphosphatase | NOD1/2, winged helix domain | P-loop containing nucleoside triphosphate hydrolase | SPRY-associated | SPRY domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PIE7
|
1140 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-16p6.1-207
(1)
|
Ensembl | 3,191 nt | ||
| mRNA |
si:dkey-16p6.1-208
(1)
|
Ensembl | 3,972 nt | ||
| mRNA |
si:dkey-16p6.1-209
(1)
|
Ensembl | 3,428 nt |
Interactions and Pathways
No data available
Plasmids
No data available