Gene

impg2b

ID
ZDB-GENE-081031-56
Name
interphotoreceptor matrix proteoglycan 2b
Symbol
impg2b Nomenclature History
Previous Names
  • impg2
  • si:ch211-213c4.2
  • si:ch211-239j15.1
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to enable heparin binding activity. Predicted to act upstream of or within visual perception. Predicted to be located in several cellular components, including cell projection; extracellular region; and interphotoreceptor matrix. Human ortholog(s) of this gene implicated in retinitis pigmentosa 56 and vitelliform macular dystrophy. Orthologous to human IMPG2 (interphotoreceptor matrix proteoglycan 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Castellini et al., 2023
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
No data available
Human Disease
Associated With impg2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 56 Alliance Retinitis pigmentosa 56 613581
vitelliform macular dystrophy Alliance Macular dystrophy, vitelliform, 5 616152
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Associated With impg2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000082 SEA domain
Domain IPR000742 EGF-like domain
Family IPR039861 Interphotoreceptor matrix proteoglycan
Homologous_superfamily IPR036364 SEA domain superfamily
1 - 4 of 4
Domain Details Per Protein
Protein Additional Resources Length EGF-like domain Interphotoreceptor matrix proteoglycan SEA domain SEA domain superfamily
UniProtKB:A0A8M9Q584 InterPro 2779
UniProtKB:A0A8M3B5Q4 InterPro 2821
UniProtKB:A0A8M9Q3E3 InterPro 2810
UniProtKB:A0A8M9PQB5 InterPro 2779
UniProtKB:A0AB32TI06 InterPro 2810
1 - 5 of 5
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 22
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA impg2b-201 (1)
Ensembl
Ensembl 278 nt
ZFIN BLAST
mRNA impg2b-202 (1)
Ensembl
Ensembl 1,061 nt
ZFIN BLAST
mRNA impg2b-203 (1)
Ensembl
Ensembl 475 nt
ZFIN BLAST
mRNA impg2b-204 (1)
Ensembl
Ensembl 1,287 nt
ZFIN BLAST
mRNA impg2b-205 (1)
Ensembl
Ensembl 274 nt
ZFIN BLAST
1 - 5 of 5
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-213C4ZFIN Curated Data
Contained inBACCH211-239J15ZFIN Curated Data
1 - 2 of 2
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_009296447 (1)9542 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:BX649245 (1)201091 nt
MegaBLAST
PolypeptideUniProtKB:A0A8M3B5Q4 (1)2821 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanIMPG23
Conserved genome location (synteny) (2)
Amino acid sequence comparison (2)
MouseImpg216
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
Citations
TSV
1 - 2 of 2
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