Gene

si:ch211-196h16.5

ID
ZDB-GENE-081029-8
Name
si:ch211-196h16.5
Symbol
si:ch211-196h16.5 Nomenclature History
Previous Names
  • Gene1133 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to be involved in intracellular signal transduction. Human ortholog(s) of this gene implicated in several diseases, including Muckle-Wells syndrome; autoimmune disease (multiple); autosomal dominant nonsyndromic deafness 34; familial cold autoinflammatory syndrome (multiple); and gestational trophoblastic neoplasm. Orthologous to several human genes including NLRP12 (NLR family pyrin domain containing 12); NLRP13 (NLR family pyrin domain containing 13); and NLRP14 (NLR family pyrin domain containing 14).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With si:ch211-196h16.5 Human Ortholog
No data available
Associated With si:ch211-196h16.5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007111 NACHT nucleoside triphosphatase
Domain IPR029495 NACHT-associated domain
Domain IPR041075 NOD1/2, winged helix domain
Domain IPR041267 NACHT, LRR and PYD domains-containing protein, helical domain HD2
Family IPR051261 NOD-like receptor
1 - 5 of 9 Show all
Domain Details Per Protein
Protein Additional Resources Length Leucine-rich repeat Leucine-rich repeat, cysteine-containing subtype Leucine-rich repeat domain superfamily NACHT-associated domain NACHT, LRR and PYD domains-containing protein, helical domain HD2 NACHT nucleoside triphosphatase NOD1/2, winged helix domain NOD-like receptor P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8N7UUW9 InterPro 1041
UniProtKB:A0AB32TRH4 InterPro 926
UniProtKB:A0AB32TVJ5 InterPro 984
1 - 3 of 3
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:ch211-196h16.5-201 (1)
Ensembl
Ensembl 4,105 nt
ZFIN BLAST
mRNA si:ch211-196h16.5-202 (1)
Ensembl
Ensembl 1,656 nt
ZFIN BLAST
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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