Gene
atrnl1a
- ID
- ZDB-GENE-081028-60
- Name
- attractin-like 1a
- Symbol
- atrnl1a Nomenclature History
- Previous Names
-
- si:ch211-270n8.2
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable Notch binding activity. Predicted to be located in membrane. Orthologous to human ATRNL1 (attractin like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa10875 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa10964 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa12259 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa12330 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa12385 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa14748 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa14797 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa17103 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa22271 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa22272 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR000859 | CUB domain |
| Domain | IPR001304 | C-type lectin-like |
| Domain | IPR002049 | Laminin-type EGF domain |
| Domain | IPR016201 | PSI domain |
| Family | IPR051568 | LZTR1/Attractin |
| Homologous_superfamily | IPR011043 | Galactose oxidase/kelch, beta-propeller |
| Homologous_superfamily | IPR015915 | Kelch-type beta propeller |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
| Homologous_superfamily | IPR016187 | C-type lectin fold |
| Homologous_superfamily | IPR035914 | Spermadhesin, CUB domain superfamily |
| Repeat | IPR002165 | Plexin repeat |
| Repeat | IPR006652 | Kelch repeat type 1 |
Domain Details Per Protein
| Protein | Additional Resources | Length | C-type lectin fold | C-type lectin-like | C-type lectin-like/link domain superfamily | CUB domain | EGF-like domain | Galactose oxidase/kelch, beta-propeller | Kelch repeat type 1 | Kelch-type beta propeller | Laminin-type EGF domain | LZTR1/Attractin | Plexin repeat | PSI domain | Spermadhesin, CUB domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1Q4X2 | InterPro | 1400 | |||||||||||||
| UniProtKB:A0A8M9PU46 | InterPro | 860 | |||||||||||||
| UniProtKB:A0AB32T5J0 | InterPro | 586 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
atrnl1a-201
(1)
|
Ensembl | 4,733 nt | ||
| mRNA |
atrnl1a-202
(1)
|
Ensembl | 2,438 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-197G14 | ZFIN Curated Data | |
| Contained in | BAC | CH211-270N8 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-262M8 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068213025 (1) | 2307 nt | ||
| Genomic | GenBank:CR762487 (2) | 219918 nt | ||
| Polypeptide | UniProtKB:F1Q4X2 (1) | 1400 aa |
- Doretto, L.B., Butzge, A.J., Nakajima, R.T., Martinez, E.R.M., de Souza, B.M., Rodrigues, M.D.S., Rosa, I.F., Ricci, J.M.B., Tovo-Neto, A., Costa, D.F., Malafaia, G., Shao, C., Nóbrega, R.H. (2022) Gdnf Acts as a Germ Cell-Derived Growth Factor and Regulates the Zebrafish Germ Stem Cell Niche in Autocrine- and Paracrine-Dependent Manners. Cells. 11(8):
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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