Gene

tenm2a

ID

ZDB-GENE-081027-5

Name

teneurin transmembrane protein 2a

Symbol

tenm2a Nomenclature History

Previous Names

tenm2
si:dkey-34l15.2

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to enable cell adhesion molecule binding activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and neuron development. Predicted to act upstream of or within signal transduction. Predicted to be located in cell projection and plasma membrane. Predicted to be active in neuron projection. Is expressed in cerebellum; hindbrain; midbrain; and olfactory bulb. Orthologous to human TENM2 (teneurin transmembrane protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from Cheung et al., 2019

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tenm2a Human Ortholog

No data available

Associated With tenm2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain
Domain	IPR009471	Teneurin intracellular, N-terminal
Domain	IPR022385	Rhs repeat-associated core
Domain	IPR028916	Tox-GHH domain
Family	IPR051216	Teneurin domain-containing protein
Homologous_superfamily	IPR008969	Carboxypeptidase-like, regulatory domain superfamily
Homologous_superfamily	IPR011042	Six-bladed beta-propeller, TolB-like
Repeat	IPR006530	YD repeat
Repeat	IPR031325	RHS repeat

Domain Details Per Protein

Protein	Length	Carboxypeptidase-like, regulatory domain superfamily	EGF-like domain	RHS repeat	Rhs repeat-associated core	Six-bladed beta-propeller, TolB-like	Teneurin domain-containing protein	Teneurin intracellular, N-terminal	Tox-GHH domain	YD repeat
UniProtKB:A0A8M9QKX8 InterPro	2772
UniProtKB:A0A8M3AP99 InterPro	2556
UniProtKB:A0A8M9PN69 InterPro	2374
UniProtKB:A0A8M3AS39 InterPro	2620
UniProtKB:A0A8M3AHZ7 InterPro	2626
UniProtKB:A0A8M9PUD3 InterPro	2366
UniProtKB:A0A8M9PZN4 InterPro	2764

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tenm2-203 (1) Ensembl	Ensembl	8,349 nt	Select Tool ZFIN BLAST
mRNA	tenm2-204 (1) Ensembl	Ensembl	7,776 nt	Select Tool ZFIN BLAST
mRNA	tenm2-206 (1) Ensembl	Ensembl	8,502 nt	Select Tool ZFIN BLAST
mRNA	tenm2a-201 (1) Ensembl	Ensembl	1,143 nt	Select Tool ZFIN BLAST
mRNA	tenm2a-202 (1) Ensembl	Ensembl	9,061 nt	Select Tool ZFIN BLAST
mRNA	tenm2a-205 (1) Ensembl	Ensembl	8,373 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations