Gene
htr2b
- ID
- ZDB-GENE-081022-57
- Name
- 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- Symbol
- htr2b Nomenclature History
- Previous Names
-
- zgc:194094
- zgc:194119
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Acts upstream of or within heart development. Predicted to be located in membrane; neuron projection; and synapse. Predicted to be active in dendrite and plasma membrane. Is expressed in brain; heart; male organism; and ventral mandibular arch. Human ortholog(s) of this gene implicated in metabolic dysfunction-associated steatohepatitis and steatotic liver disease. Orthologous to human HTR2B (5-hydroxytryptamine receptor 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kent et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | 5-Hydroxytryptamine 2B receptor | 5-hydroxytryptamine receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|---|
| UniProtKB:Q0GH74 | InterPro | 443 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available