ZFIN is now using GRCz12tu for Genomic Data
Gene
mical1
- ID
- ZDB-GENE-081022-3
- Name
- microtubule associated monooxygenase, calponin and LIM domain containing 1
- Symbol
- mical1 Nomenclature History
- Previous Names
-
- zgc:171928
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including F-actin monooxygenase activity; FAD binding activity; and NAD(P)H oxidase H2O2-forming activity. Predicted to be involved in actin filament depolymerization and sulfur oxidation. Predicted to be located in cytosol; endosome membrane; and midbody. Orthologous to human MICAL1 (microtubule associated monooxygenase, calponin and LIM domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Xue et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001715 | Calponin homology domain |
| Domain | IPR001781 | Zinc finger, LIM-type |
| Domain | IPR002938 | FAD-binding domain |
| Domain | IPR022735 | bMERB domain |
| Domain | IPR057494 | [F-actin]-monooxygenase MICAL1-3-like, Rossman domain |
| Family | IPR050540 | F-actin Monooxygenase Mical |
| Homologous_superfamily | IPR036188 | FAD/NAD(P)-binding domain superfamily |
| Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | bMERB domain | Calponin homology domain | CH domain superfamily | F-actin Monooxygenase Mical | [F-actin]-monooxygenase MICAL1-3-like, Rossman domain | FAD-binding domain | FAD/NAD(P)-binding domain superfamily | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7F9T0 | InterPro | |||||||||
| UniProtKB:E5F2M3 | InterPro | 847 | ||||||||
| UniProtKB:G0WKK0 | InterPro | 322 | ||||||||
| UniProtKB:A0A9U5FS91 | InterPro | 1214 | ||||||||
| UniProtKB:A0AC58IKJ1 | InterPro | 1214 | ||||||||
| UniProtKB:A0AC58IKR1 | InterPro | 1214 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mical1-202
(1)
|
Ensembl | 3,920 nt | ||
| mRNA |
mical1-203
(1)
|
Ensembl | 4,002 nt | ||
| mRNA |
mical1-204
(1)
|
Ensembl | 4,513 nt | ||
| ncRNA |
mical1-002
(1)
|
Ensembl | 1,212 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers