Gene
ccl20a.3
- ID
- ZDB-GENE-081022-193
- Name
- chemokine (C-C motif) ligand 20a, duplicate 3
- Symbol
- ccl20a.3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable chemokine activity. Acts upstream of or within defense response to bacterium and immune response. Predicted to be located in extracellular space. Is expressed in liver. Orthologous to human CCL20 (C-C motif chemokine ligand 20).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CC chemokine, conserved site | Chemokine beta/gamma/delta | Chemokine interleukin-8-like domain | Chemokine interleukin-8-like superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:B3DGM0 | InterPro | 99 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ccl20a.3-201
(1)
|
Ensembl | 632 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-320I17 | ZFIN Curated Data | |
| Contained in | BAC | CH211-153N15 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:195195 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:195209 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001136254 (1) | 631 nt | ||
| Genomic | GenBank:CR407590 (1) | 167238 nt | ||
| Polypeptide | UniProtKB:B3DGM0 (1) | 99 aa |
| Species | Symbol | Chromosome | Accession # | Evidence |
|---|---|---|---|---|
| Human | CCL20 | 2 | Amino acid sequence comparison (1) |
- Ernst, A., Piragyte, I., Mp, A.M., Le, N.D., Grandgirard, D., Leib, S.L., Oates, A., Mercader, N. (2023) Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform. Scientific Reports. 13:1703717037
- Luckner, B., Essfeld, F., Ayobahan, S.U., Richling, E., Eilebrecht, E., Eilebrecht, S. (2023) Transcriptomic profiling of TLR-7-mediated immune-challenge in zebrafish embryos in the presence and absence of glucocorticoid-induced immunosuppression. Ecotoxicology and environmental safety. 266:115570115570
- Choi, S.S.A., Chan, H.H., Chan, C.M., Wang, X., Webb, S.E., Leung, K.W., Tsim, K.W.K., Miller, A.L. (2022) Neuromasts and Olfactory Organs of Zebrafish Larvae Represent Possible Sites of SARS-CoV-2 Pseudovirus Host Cell Entry. Journal of virology. 96(24):e0141822
- Laghi, V., Rezelj, V., Boucontet, L., Frétaud, M., Da Costa, B., Boudinot, P., Salinas, I., Lutfalla, G., Vignuzzi, M., Levraud, J.P. (2022) Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder. Frontiers in cellular and infection microbiology. 12:790851
- Rawson, A., Saxena, V., Gao, H., Hooks, J., Xuei, X., McGuire, P., Hato, T., Hains, D.S., Anderson, R.M., Schwaderer, A.L. (2022) A Pilot Single Cell Analysis of the Zebrafish Embryo Cellular Responses to Uropathogenic Escherichia coli Infection. Pathogens & immunity. 7:1-18
- Yu, L., Li, C.H., Chen, J. (2019) A novel CC chemokine ligand 2 like gene from ayu Plecoglossus altivelis is involved in the innate immune response against to Vibrio anguillarum. Fish & shellfish immunology. 87:886-896
- Zhang, Q., Ji, C., Ren, J., Zhang, Q., Dong, X., Zu, Y., Jia, L., Li, W. (2018) Differential transcriptome analysis of zebrafish (Danio rerio) larvae challenged by Vibrio parahaemolyticus. Journal of fish diseases. 41(7):1049-1062
- Zhou, T., Li, N., Jin, Y., Zeng, Q., Prabowo, W., Liu, Y., Tian, C., Bao, L., Liu, S., Yuan, Z., Fu, Q., Gao, S., Gao, D., Dunham, R., Shubin, N.H., Liu, Z. (2018) Chemokine C-C motif ligand 33 is a key regulator of teleost fish barbel development. Proceedings of the National Academy of Sciences of the United States of America. 115(22):E5018-E5027
- Blaser, B.W., Moore, J.L., Hagedorn, E.J., Li, B., Riquelme, R., Lichtig, A., Yang, S., Zhou, Y., Tamplin, O.J., Binder, V., Zon, L.I. (2017) CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of experimental medicine. 214(4):1011
- Nomiyama, H., Osada, N., and Yoshie, O. (2013) Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history. Genes to cells : devoted to molecular & cellular mechanisms. 18(1):1-16
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