Gene
knstrn
- ID
- ZDB-GENE-081022-187
- Name
- kinetochore localized astrin (SPAG5) binding protein
- Symbol
- knstrn Nomenclature History
- Previous Names
-
- zgc:195152 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to be involved in mitotic sister chromatid segregation; regulation of attachment of spindle microtubules to kinetochore; and spindle organization. Predicted to act upstream of or within chromosome segregation. Predicted to be active in kinetochore and microtubule cytoskeleton. Human ortholog(s) of this gene implicated in actinic keratosis and skin squamous cell carcinoma. Orthologous to human KNSTRN (kinetochore localized astrin (SPAG5) binding protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Roifman-Chitayat syndrome, digenic | 613328 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR033373 | Small kinetochore-associated protein |
Domain Details Per Protein
| Protein | Length | Small kinetochore-associated protein |
|---|---|---|
|
UniProtKB:B3DIM7
|
197 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
knstrn-201
(1)
|
Ensembl | 1,124 nt |
Interactions and Pathways
No data available
Plasmids
No data available