Gene
plekhm2
- ID
- ZDB-GENE-081022-169
- Name
- pleckstrin homology domain containing, family M (with RUN domain) member 2
- Symbol
- plekhm2 Nomenclature History
- Previous Names
-
- zgc:194971
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have kinesin binding activity. Predicted to be involved in several processes, including Golgi organization; lysosome localization; and positive regulation of membrane tubulation. Predicted to localize to endosome membrane. Orthologous to human PLEKHM2 (pleckstrin homology and RUN domain containing M2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR004012 | RUN domain |
| Domain | IPR047327 | PLEKHM2, RUN domain |
| Family | IPR053015 | Pleckstrin homology domain-containing protein M2 |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR037213 | RUN domain superfamily |
Domain Details Per Protein
| Protein | Length | PH-like domain superfamily | Pleckstrin homology domain | Pleckstrin homology domain-containing protein M2 | PLEKHM2, RUN domain | RUN domain | RUN domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AYE3
|
974 | ||||||
|
UniProtKB:B3DJE5
|
994 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
plekhm2-201
(1)
|
Ensembl | 3,335 nt | ||
| ncRNA |
plekhm2-002
(1)
|
Ensembl | 602 nt |
Interactions and Pathways
No data available
Plasmids
No data available