Gene
plekhm2
- ID
- ZDB-GENE-081022-169
- Name
- pleckstrin homology domain containing, family M (with RUN domain) member 2
- Symbol
- plekhm2 Nomenclature History
- Previous Names
-
- zgc:194971
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable kinesin binding activity. Predicted to be involved in Golgi organization; lysosome localization; and regulation of protein localization. Predicted to be located in endomembrane system and lysosomal membrane. Predicted to be active in endosome membrane. Orthologous to human PLEKHM2 (pleckstrin homology and RUN domain containing M2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR004012 | RUN domain |
| Domain | IPR047327 | PLEKHM2, RUN domain |
| Family | IPR053015 | Pleckstrin homology domain-containing protein M2 |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR037213 | RUN domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | PH-like domain superfamily | Pleckstrin homology domain | Pleckstrin homology domain-containing protein M2 | PLEKHM2, RUN domain | RUN domain | RUN domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AYE3 | InterPro | 974 | ||||||
| UniProtKB:B3DJE5 | InterPro | 994 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
plekhm2-201
(1)
|
Ensembl | 3,335 nt | ||
| ncRNA |
plekhm2-002
(1)
|
Ensembl | 602 nt |
Interactions and Pathways
No data available
Plasmids
No data available