ZFIN ID: ZDB-GENE-081022-158
Gene Name: interferon gamma receptor 1
Gene Symbol: ifngr1    Nomenclature History

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Previous Names: IFNGR1-2 (1), crfb17, zgc:194858, zgc:194873

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have cytokine receptor activity. Involved in endothelial to hematopoietic transition and hemopoiesis. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in brain; cardiovascular system; gill; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in asthma; hepatitis B; primary immunodeficiency disease; and tuberculosis. Orthologous to human IFNGR1 (interferon gamma receptor 1).
Genome Resources: Alliance (1),  Gene:571368 (1),  Ensembl(GRCz11):ENSDARG00000074771 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
s986 Indel Unknown Unknown TALEN
s987 Small Deletion Unknown Unknown TALEN
sa1747 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39701 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-ifngr1
    1
    CRISPR2-ifngr1
    1
    MO1-ifngr1 N/A 2
    MO2-ifngr1 N/A 3
    MO3-ifngr1 N/A 1
    MO4-ifngr1 N/A 1
    TALEN1-ifngr1 1
    DISEASE ASSOCIATED WITH ifngr1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ifngr1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endothelial to hematopoietic transition (more)
    Cellular Component integral component of membrane (more)
    Molecular Function cytokine receptor activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ifngr1-201 (1)    Ensembl 1850
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ifngr1 No data available
    MARKER RELATIONSHIPS
    ifngr1 Contained in: [BAC] CH73-59B17 (1)
    ifngr1 Encodes: [cDNA] MGC:194858 (1), MGC:194873 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001135979 (1) 1850 nt
    Genomic GenBank:FP017162 (1) 76731 nt
    Select Tool
    Polypeptide UniProtKB:F6NZK1 (1) 394 aa
    Sequence Information (all 18)
    ORTHOLOGY for ifngr1 ( Chr: 1 )
    CITATIONS (28)