| ZFIN ID: ZDB-GENE-081022-158 |
| Gene Name: | interferon gamma receptor 1 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene Symbol: | ifngr1 Nomenclature History |
{{control.fieldName}} Edit
Attributions
|
||||||||||||
| Previous Names: | IFNGR1-2 (1), crfb17, zgc:194858, zgc:194873 | |||||||||||||
Add new Alias
Attributions for Alias: {{control.newAlias}}
Delete Alias:(Including Attributions) |
||||||||||||||
| Gene Type: | protein_coding_gene | |||||||||||||
| Location: | Chr: 1 Mapping Details/Browsers | |||||||||||||
| Description: | Predicted to have cytokine receptor activity. Involved in endothelial to hematopoietic transition and hemopoiesis. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in brain; cardiovascular system; gill; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in asthma; hepatitis B; primary immunodeficiency disease; and tuberculosis. Orthologous to human IFNGR1 (interferon gamma receptor 1). | |||||||||||||
| Genome Resources: | Alliance (1), Gene:571368 (1), Ensembl(GRCz11):ENSDARG00000074771 (2) | |||||||||||||
| All Expression Data: | 6 figures from 5 publications |
| Wild-type Stages, Structures: | Pharyngula:Prim-25 (36.0h-42.0h) to Adult (90d-730d, breeding adult) |
MUTATIONS AND SEQUENCE TARGETING REAGENTS
| Allele | Type | Localization | Consequence | Mutagen | Suppliers |
|---|---|---|---|---|---|
| s986 | Indel | Unknown | Unknown | TALEN | |
| s987 | Small Deletion | Unknown | Unknown | TALEN | |
| sa1747 | Point Mutation | Unknown | Premature Stop | ENU |
|
| sa39701 | Point Mutation | Unknown | Premature Stop | ENU |
|
Sequence Targeting Reagents
| Targeting Reagent | Created Alleles | Publications |
|---|---|---|
| CRISPR1-ifngr1 |
|
1 |
| CRISPR2-ifngr1 |
|
1 |
| MO1-ifngr1 | N/A | 2 |
| MO2-ifngr1 | N/A | 3 |
| MO3-ifngr1 | N/A | 1 |
| MO4-ifngr1 | N/A | 1 |
| TALEN1-ifngr1 | 1 |
PHENOTYPE
| Data: | 3 figures from Sawamiphak et al., 2014 |
| Observed in: |
GENE ONTOLOGY
| Ontology | GO Term |
|---|---|
| Biological Process | endothelial to hematopoietic transition (more) |
| Cellular Component | integral component of membrane (more) |
| Molecular Function | cytokine receptor activity (more) |
| Type | Name | Length (nt) | Analysis | |
|---|---|---|---|---|
| mRNA |
ifngr1-201
(1)
|
1850 |
Select Tool
|
| Browsers: UCSC, NCBI, Ensembl, ZFIN |
INTERACTIONS AND PATHWAYS
ANTIBODIES
No data available
PLASMIDS
No data available
CONSTRUCTS WITH SEQUENCES FROM ifngr1
No data available
MARKER RELATIONSHIPS
| ifngr1 Contained in: | [BAC] CH73-59B17 (1) |
| ifngr1 Encodes: | [cDNA] MGC:194858 (1), MGC:194873 (1) |
SEQUENCE INFORMATION
| Type | Accession # | Length (nt/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_001135979 (1) | 1850 nt |
Select Tool
|
| Genomic | GenBank:FP017162 (1) | 76731 nt | |
| Polypeptide | UniProtKB:F6NZK1 (1) | 394 aa |
Select Tool
|
ORTHOLOGY for ifngr1 (
Chr:
1
)
CITATIONS (28)