ZFIN is now using GRCz12tu for Genomic Data
Gene
adrb1
- ID
- ZDB-GENE-081022-145
- Name
- adrenoceptor beta 1
- Symbol
- adrb1 Nomenclature History
- Previous Names
-
- zgc:194728
- zgc:194731
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable beta1-adrenergic receptor activity. Acts upstream of or within establishment of endothelial barrier; regulation of heart rate; and venous blood vessel morphogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adipose tissue; eye; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including chronic obstructive pulmonary disease; heart disease (multiple); hypertension (multiple); low tension glaucoma; and sleep disorder (multiple). Orthologous to human ADRB1 (adrenoceptor beta 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Adrenoceptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
| UniProtKB:B3DHM6 | InterPro | 390 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers