Gene

tubgcp4

ID

ZDB-GENE-081022-124

Name

tubulin gamma complex component 4

Symbol

tubgcp4 Nomenclature History

Previous Names

zgc:194561
zgc:194580

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to contribute to microtubule minus-end binding activity. Involved in retinal cone cell differentiation and retinal rod cell differentiation. Predicted to localize to centrosome; equatorial microtubule organizing center; and gamma-tubulin complex. Human ortholog(s) of this gene implicated in microcephaly and chorioretinopathy 3. Orthologous to human TUBGCP4 (tubulin gamma complex associated protein 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Scheidecker et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Scheidecker et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tubgcp4 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
microcephaly and chorioretinopathy 3	Alliance	Microcephaly and chorioretinopathy, autosomal recessive, 3	616335

Associated With tubgcp4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040457	Gamma tubulin complex component, C-terminal
Domain	IPR041470	Gamma tubulin complex component protein, N-terminal
Family	IPR007259	Gamma-tubulin complex component protein
Homologous_superfamily	IPR042241	Gamma-tubulin complex component, C-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Gamma tubulin complex component, C-terminal	Gamma-tubulin complex component, C-terminal domain superfamily	Gamma-tubulin complex component protein	Gamma tubulin complex component protein, N-terminal
UniProtKB:B3DIU9 InterPro	668

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tubgcp4-201 (1) Ensembl	Ensembl	5,829 nt	Select Tool ZFIN BLAST
mRNA	tubgcp4-202 (1) Ensembl	Ensembl	3,185 nt	Select Tool
ncRNA	tubgcp4-002 (1) Ensembl	Ensembl	436 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations