Gene

tubgcp4

ID
ZDB-GENE-081022-124
Name
tubulin, gamma complex associated protein 4
Symbol
tubgcp4 Nomenclature History
Previous Names
  • zgc:194561
  • zgc:194580
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Is predicted to contribute to microtubule minus-end binding activity. Involved in retinal cone cell differentiation and retinal rod cell differentiation. Predicted to localize to centrosome; equatorial microtubule organizing center; and gamma-tubulin complex. Human ortholog(s) of this gene implicated in microcephaly and chorioretinopathy 3. Orthologous to human TUBGCP4 (tubulin gamma complex associated protein 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Scheidecker et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Scheidecker et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tubgcp4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
microcephaly and chorioretinopathy 3 Alliance Microcephaly and chorioretinopathy, autosomal recessive, 3 616335
Associated With tubgcp4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR040457 Gamma tubulin complex component, C-terminal
Domain IPR041470 Gamma tubulin complex component protein, N-terminal
Family IPR007259 Gamma-tubulin complex component protein
Homologous_superfamily IPR042241 Gamma-tubulin complex, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Gamma tubulin complex component, C-terminal Gamma-tubulin complex component protein Gamma tubulin complex component protein, N-terminal Gamma-tubulin complex, C-terminal domain superfamily
UniProtKB:B3DIU9 668
UniProtKB:F6PFE9 697
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations