Gene

prox2

ID
ZDB-GENE-081003-3
Name
prospero homeobox 2
Symbol
prox2 Nomenclature History
Previous Names
  • prox1-like (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have DNA binding activity. Predicted to be involved in lymphangiogenesis; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including gonad; hindbrain neural keel; immature eye; liver; and nervous system. Orthologous to human PROX2 (prospero homeobox 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Pistocchi et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prox2 Human Ortholog
No data available
Associated With prox2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR023082 Homeo-prospero domain
Family IPR039350 Prospero homeodomain family
Homologous_superfamily IPR009057 Homedomain-like superfamily
Homologous_superfamily IPR037131 Homeo-prospero domain superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeo-prospero domain Homeo-prospero domain superfamily Prospero homeodomain family
UniProtKB:B2BHT6 582
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA prox2-201 (1) Ensembl 2,432 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations