Gene
exosc1
- ID
- ZDB-GENE-080926-3
- Name
- exosome component 1
- Symbol
- exosc1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Predicted to act upstream of or within RNA processing. Predicted to be located in nucleolus. Predicted to be part of nuclear exosome (RNase complex). Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1F. Orthologous to human EXOSC1 (exosome component 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Cabrera-Quio et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pontocerebellar hypoplasia type 1F | Alliance | ?Pontocerebellar hypoplasia, type 1F | 619304 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Exosome complex component Csl4 | Exosome complex component CSL4, C-terminal | Exosome complex component, N-terminal domain | Nucleic acid-binding, OB-fold | S1 domain |
|---|---|---|---|---|---|---|
|
UniProtKB:B8A4H5
|
194 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
exosc1-201
(1)
|
Ensembl | 612 nt |
Interactions and Pathways
No data available
Plasmids
No data available