Gene

nsun6

ID

ZDB-GENE-080808-8

Name

NOP2/Sun RNA methyltransferase 6

Symbol

nsun6 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have RNA binding activity and methyltransferase activity. Predicted to be involved in RNA methylation. Orthologous to human NSUN6 (NOP2/Sun RNA methyltransferase 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nsun6 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal recessive intellectual developmental disorder 82	Alliance	Intellectual developmental disorder, autosomal recessive 82	620779

Associated With nsun6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018314	RsmB/NOL1/NOP2-like, conserved site
Domain	IPR001678	SAM-dependent methyltransferase RsmB-F/NOP2-type domain
Domain	IPR049560	SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core
Family	IPR023267	RNA (C5-cytosine) methyltransferase
Homologous_superfamily	IPR015947	PUA-like superfamily
Homologous_superfamily	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily
Homologous_superfamily	IPR036974	PUA domain superfamily

Domain Details Per Protein

Protein	Length	PUA domain superfamily	PUA-like superfamily	RNA (C5-cytosine) methyltransferase	RsmB/NOL1/NOP2-like, conserved site	S-adenosyl-L-methionine-dependent methyltransferase superfamily	SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core	SAM-dependent methyltransferase RsmB-F/NOP2-type domain
UniProtKB:A0A0R4IAT4 InterPro	459
UniProtKB:A0A8M6Z0B3 InterPro	458

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	nsun6-201 (1) Ensembl	Ensembl	1,702 nt	Select Tool
mRNA	nsun6-202 (1) Ensembl	Ensembl	1,603 nt	Select Tool ZFIN BLAST
mRNA	nsun6-203 (1) Ensembl	Ensembl	1,796 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations