Gene
nsun6
- ID
- ZDB-GENE-080808-8
- Name
- NOP2/Sun RNA methyltransferase 6
- Symbol
- nsun6 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity and RNA methyltransferase activity. Predicted to be involved in RNA methylation. Predicted to act upstream of or within methylation. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 82. Orthologous to human NSUN6 (NOP2/Sun RNA methyltransferase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 82 | Alliance | Intellectual developmental disorder, autosomal recessive 82 | 620779 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018314 | RsmB/NOL1/NOP2-like, conserved site |
| Domain | IPR001678 | SAM-dependent methyltransferase RsmB-F/NOP2-type domain |
| Domain | IPR049560 | SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core |
| Family | IPR023267 | RNA (C5-cytosine) methyltransferase |
| Homologous_superfamily | IPR015947 | PUA-like superfamily |
| Homologous_superfamily | IPR029063 | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
| Homologous_superfamily | IPR036974 | PUA domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | PUA domain superfamily | PUA-like superfamily | RNA (C5-cytosine) methyltransferase | RsmB/NOL1/NOP2-like, conserved site | S-adenosyl-L-methionine-dependent methyltransferase superfamily | SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core | SAM-dependent methyltransferase RsmB-F/NOP2-type domain |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IAT4 | InterPro | 459 | |||||||
| UniProtKB:A0A8M6Z0B3 | InterPro | 458 |
Interactions and Pathways
No data available
Plasmids
No data available