Gene
skilb
- ID
- ZDB-GENE-080723-40
- Name
- SKI-like proto-oncogene b
- Symbol
- skilb Nomenclature History
- Previous Names
-
- zgc:193698
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Predicted to be involved in negative regulation of BMP signaling pathway. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be active in nucleus. Orthologous to human SKIL (SKI like proto-oncogene).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003380 | SKI/SNO/DAC domain |
| Domain | IPR014890 | c-SKI SMAD4-binding domain |
| Family | IPR023216 | Transcription regulator SKI/SnoN |
| Homologous_superfamily | IPR009061 | Putative DNA-binding domain superfamily |
| Homologous_superfamily | IPR010919 | SAND-like domain superfamily |
| Homologous_superfamily | IPR037000 | Ski-like, DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | c-SKI SMAD4-binding domain | Putative DNA-binding domain superfamily | SAND-like domain superfamily | Ski-like, DNA-binding domain superfamily | SKI/SNO/DAC domain | Transcription regulator SKI/SnoN |
|---|---|---|---|---|---|---|---|
|
UniProtKB:E7FGJ1
|
624 | ||||||
|
UniProtKB:B3DGU8
|
629 |
Interactions and Pathways
No data available
Plasmids
No data available