Gene

prdm1b

ID

ZDB-GENE-080618-2

Name

PR domain containing 1b, with ZNF domain

Symbol

prdm1b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate commitment and regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm and nucleus. Is expressed in retina and somite. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung adenocarcinoma. Orthologous to human PRDM1 (PR/SET domain 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Sun et al., 2008

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With prdm1b Human Ortholog

No data available

Associated With prdm1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001214	SET domain
Domain	IPR044413	PRDM1, PR/SET domain

Domain Details Per Protein

Protein	Length	PRDM1, PR/SET domain	SET domain
UniProtKB:A5XCE7 InterPro	134
UniProtKB:A0A0R4IRK0 InterPro	377
UniProtKB:A0A2R8Q3S6 InterPro	471

Transcripts

Genome Browsers: No data available

No data available

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations