Gene

nsmfb

ID
ZDB-GENE-080603-4
Name
NMDA receptor synaptonuclear signaling and neuronal migration factor b
Symbol
nsmfb Nomenclature History
Previous Names
  • nelf
  • nelfb
  • si:ch73-239f21.1
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Involved in positive regulation of axon extension and positive regulation of neuron migration. Predicted to localize to several cellular components, including dendrite; nucleus; and postsynaptic density. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 7 with or without anosmia and hypogonadotropic hypogonadism 9 with or without anosmia. Is expressed in brain and olfactory epithelium. Orthologous to human NSMF (NMDA receptor synaptonuclear signaling and neuronal migration factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Palevitch et al., 2009
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nsmfb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 9 with or without anosmia Alliance Hypogonadotropic hypogonadism 9 with or without anosmia 614838
Associated With nsmfb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR033374 NMDA receptor synaptonuclear signalling and neuronal migration factor
Domain Details Per Protein
Protein Length NMDA receptor synaptonuclear signalling and neuronal migration factor
UniProtKB:A0A8M9Q3Q1 579
UniProtKB:A0A0R4INI9 568
UniProtKB:A0A8M9PY12 593
UniProtKB:B8PYG1 570
UniProtKB:A0A8M9Q8Z5 560
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nsmfb-201 (1) Ensembl 934 nt
mRNA nsmfb-202 (1) Ensembl 6,760 nt
mRNA nsmfb-203 (1) Ensembl 1,206 nt
mRNA nsmfb-204 (1) Ensembl 1,713 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations