Gene
setd1bb
- ID
- ZDB-GENE-080522-1
- Name
- SET domain containing 1B, histone lysine methyltransferase b
- Symbol
- setd1bb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable histone H3K4 methyltransferase activity. Predicted to act upstream of or within chromatin organization and methylation. Predicted to be located in chromosome and nucleus. Predicted to be part of Set1C/COMPASS complex. Orthologous to human SETD1B (SET domain containing 1B, histone lysine methyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sun et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder with seizures and language delay | 619000 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR001214 | SET domain |
| Domain | IPR003616 | Post-SET domain |
| Domain | IPR024657 | COMPASS complex Set1 subunit, N-SET domain |
| Domain | IPR037841 | Histone-lysine N-methyltransferase SETD1A/B-like, SET domain |
| Family | IPR044570 | Histone-lysine N-methyltransferase Set1-like |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
| Homologous_superfamily | IPR046341 | SET domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | COMPASS complex Set1 subunit, N-SET domain | Histone-lysine N-methyltransferase Set1-like | Histone-lysine N-methyltransferase SETD1A/B-like, SET domain | Nucleotide-binding alpha-beta plait domain superfamily | Post-SET domain | RNA-binding domain superfamily | RNA recognition motif domain | SET domain | SET domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9P9Z7 | InterPro | 1215 | |||||||||
| UniProtKB:A0A8M3BBX9 | InterPro | 1859 | |||||||||
| UniProtKB:A0A8M9PZL0 | InterPro | 1859 | |||||||||
| UniProtKB:A0A8M3AVC1 | InterPro | 1215 | |||||||||
| UniProtKB:A0AB32TI41 | InterPro | 1491 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available