Gene

bcar3

ID

ZDB-GENE-080513-4

Name

BCAR3 adaptor protein, NSP family member

Symbol

bcar3 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of peptidyl-serine phosphorylation. Orthologous to human BCAR3 (BCAR3 adaptor protein, NSP family member).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bcar3 Human Ortholog

No data available

Associated With bcar3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000980	SH2 domain
Domain	IPR001660	Sterile alpha motif domain
Domain	IPR001895	Ras guanine-nucleotide exchange factors catalytic domain
Domain	IPR044102	SHEP1/BCAR3/NSP1, SH2 domain
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily
Homologous_superfamily	IPR023578	Ras guanine nucleotide exchange factor domain superfamily
Homologous_superfamily	IPR036860	SH2 domain superfamily
Homologous_superfamily	IPR036964	Ras guanine-nucleotide exchange factor, catalytic domain superfamily

Domain Details Per Protein

Protein	Length	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Ras guanine nucleotide exchange factor domain superfamily	Ras guanine-nucleotide exchange factors catalytic domain	SH2 domain	SH2 domain superfamily	SHEP1/BCAR3/NSP1, SH2 domain	Sterile alpha motif domain	Sterile alpha motif/pointed domain superfamily
UniProtKB:A0A8M3BBM9 InterPro	756
UniProtKB:F1R3Z4 InterPro	918
UniProtKB:A0A8M2BEX1 InterPro	912
UniProtKB:A0A8M9QDU4 InterPro	727
UniProtKB:B0UXN8 InterPro	746
UniProtKB:A0A8M2BED0 InterPro	841

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	bcar3-202 (1) Ensembl	Havana	655 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	bcar3-203 (1) Ensembl	Havana	2693 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	bcar3-204 (1) Ensembl	Havana	537 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	bcar3-205 (1) Ensembl	Havana	2390 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations