Gene

dhx40

ID

ZDB-GENE-080507-1

Name

DEAH (Asp-Glu-Ala-His) box polypeptide 40

Symbol

dhx40 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to localize to spliceosomal complex. Orthologous to human DHX40 (DEAH-box helicase 40).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Williams et al., 2016

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dhx40 Human Ortholog

No data available

Associated With dhx40 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR002464	DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR007502	Helicase-associated domain
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR011709	DEAD-box helicase, OB fold
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR048333	Helicase associated domain (HA2), winged-helix domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	DEAD-box helicase, OB fold	DEAD/DEAH box helicase domain	DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site	Helicase-associated domain	Helicase associated domain (HA2), winged-helix domain	Helicase, C-terminal domain-like	Helicase superfamily 1/2, ATP-binding domain	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M9NYI7 InterPro	733
UniProtKB:A0A8M9PSL1 InterPro	109
UniProtKB:A0A8M9PIH1 InterPro	734

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dhx40-201 (1) Ensembl	Havana	7465 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations