Gene
dmgdh
- ID
- ZDB-GENE-080227-8
- Name
- dimethylglycine dehydrogenase
- Symbol
- dmgdh Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have dimethylglycine dehydrogenase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to mitochondrial matrix. Orthologous to human DMGDH (dimethylglycine dehydrogenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Dimethylglycine dehydrogenase deficiency | 605850 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006076 | FAD dependent oxidoreductase |
| Domain | IPR006222 | Aminomethyltransferase, folate-binding domain |
| Domain | IPR013977 | Glycine cleavage T-protein, C-terminal barrel domain |
| Domain | IPR032503 | FAD dependent oxidoreductase, central domain |
| Family | IPR028896 | Aminomethyltransferase-like |
| Homologous_superfamily | IPR027266 | GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 |
| Homologous_superfamily | IPR029043 | Glycine cleavage T-protein/YgfZ, C-terminal |
| Homologous_superfamily | IPR036188 | FAD/NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Aminomethyltransferase, folate-binding domain | Aminomethyltransferase-like | FAD dependent oxidoreductase | FAD dependent oxidoreductase, central domain | FAD/NAD(P)-binding domain superfamily | Glycine cleavage T-protein, C-terminal barrel domain | Glycine cleavage T-protein/YgfZ, C-terminal | GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PCV7
|
862 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available