Gene

slc9a1b

ID

ZDB-GENE-080225-42

Name

solute carrier family 9 member A1b

Symbol

slc9a1b Nomenclature History

Previous Names

nhe1 (1)
slc9a1

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to act upstream of or within regulation of pH; sodium ion transport; and transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in blood and gill. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 19 and congestive heart failure. Orthologous to human SLC9A1 (solute carrier family 9 member A1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Yan et al., 2007

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc9a1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal recessive spinocerebellar ataxia 19	Alliance	Lichtenstein-Knorr syndrome	616291

Associated With slc9a1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006153	Cation/H+ exchanger
Domain	IPR032103	Sodium/hydrogen exchanger, regulatory region
Family	IPR001970	Sodium/hydrogen exchanger 1-like
Family	IPR004709	Na+/H+ exchanger
Family	IPR018422	Cation/H+ exchanger, CPA1 family