ZFIN is now using GRCz12tu for Genomic Data
Gene
arhgef25b
- ID
- ZDB-GENE-080225-17
- Name
- Rho guanine nucleotide exchange factor (GEF) 25b
- Symbol
- arhgef25b Nomenclature History
- Previous Names
-
- im:7156160
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in axon guidance. Predicted to be active in cytoplasm and plasma membrane. Predicted to be extrinsic component of membrane. Is expressed in ball; epidermis; extension; median fin fold; and periderm. Orthologous to human ARHGEF25 (Rho guanine nucleotide exchange factor 25).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7156160 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000219 | Dbl homology domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR055251 | SOS1/NGEF-like, PH domain |
| Family | IPR051336 | Rho GTPase-activating Guanine Nucleotide Exchange Factors |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Dbl homology (DH) domain superfamily | Dbl homology domain | PH-like domain superfamily | Pleckstrin homology domain | Rho GTPase-activating Guanine Nucleotide Exchange Factors | SOS1/NGEF-like, PH domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8Q2V3 | InterPro | 625 | ||||||
| UniProtKB:E7FF78 | InterPro | 625 | ||||||
| UniProtKB:A0A8N7TE15 | InterPro | 581 | ||||||
| UniProtKB:A0A8M9QG91 | InterPro | 581 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arhgef25b-201
(1)
|
Ensembl | 2,240 nt | ||
| mRNA |
arhgef25b-202
(1)
|
Ensembl | 716 nt | ||
| mRNA |
arhgef25b-203
(1)
|
Ensembl | 1,878 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers