Gene

arhgef25b

ID
ZDB-GENE-080225-17
Name
Rho guanine nucleotide exchange factor (GEF) 25b
Symbol
arhgef25b Nomenclature History
Previous Names
  • im:7156160
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in axon guidance. Predicted to be active in cytoplasm and plasma membrane. Predicted to be extrinsic component of membrane. Is expressed in ball; epidermis; extension; median fin fold; and periderm. Orthologous to human ARHGEF25 (Rho guanine nucleotide exchange factor 25).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arhgef25b Human Ortholog
No data available
Associated With arhgef25b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000219 Dbl homology domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR055251 SOS1/NGEF-like, PH domain
Family IPR051336 Rho GTPase-activating Guanine Nucleotide Exchange Factors
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Domain Details Per Protein
Protein Additional Resources Length Dbl homology (DH) domain superfamily Dbl homology domain PH-like domain superfamily Pleckstrin homology domain Rho GTPase-activating Guanine Nucleotide Exchange Factors SOS1/NGEF-like, PH domain
UniProtKB:A0A2R8Q2V3 InterPro 625
UniProtKB:E7FF78 InterPro 625
UniProtKB:A0A8N7TE15 InterPro 581
UniProtKB:A0A8M9QG91 InterPro 581
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA arhgef25b-201 (1)
Ensembl
Ensembl 2,240 nt
ZFIN BLAST
mRNA arhgef25b-202 (1)
Ensembl
Ensembl 716 nt
ZFIN BLAST
mRNA arhgef25b-203 (1)
Ensembl
Ensembl 1,878 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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