Gene

kdm2bb

ID

ZDB-GENE-080225-13

Name

lysine (K)-specific demethylase 2Bb

Symbol

kdm2bb Nomenclature History

Previous Names

jhdm1B (1)
fbxl10 (1)
im:7154787

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have DNA binding activity and zinc ion binding activity. Involved in embryonic cranial skeleton morphogenesis; hematopoietic progenitor cell differentiation; and rRNA transcription. Is expressed in central nervous system and retinal photoreceptor layer. Orthologous to human KDM2B (lysine demethylase 2B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7154787 (16 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kdm2bb Human Ortholog

No data available

Associated With kdm2bb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001810	F-box domain
Domain	IPR002857	Zinc finger, CXXC-type
Domain	IPR003347	JmjC domain
Domain	IPR019787	Zinc finger, PHD-finger
Domain	IPR041070	Jumonji, helical domain
Domain	IPR041667	Cupin-like domain 8
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Repeat	IPR006553	Leucine-rich repeat, cysteine-containing subtype

Domain Details Per Protein

Protein	Length	Cupin-like domain 8	F-box domain	JmjC domain	Jumonji, helical domain	Leucine-rich repeat, cysteine-containing subtype	Leucine-rich repeat domain superfamily	Zinc finger, CXXC-type	Zinc finger, FYVE/PHD-type	Zinc finger, PHD-finger	Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A8M3B6L0 InterPro	778
UniProtKB:A0A8M9PAJ6 InterPro	513
UniProtKB:A0A8M9PLZ6 InterPro	313
UniProtKB:A0A8M9Q6R7 InterPro	1263
UniProtKB:A0A8M9QLB5 InterPro	1063
UniProtKB:F6P9Q3 InterPro	1260