ZFIN is now using GRCz12tu for Genomic Data
Gene
kdm2bb
- ID
- ZDB-GENE-080225-13
- Name
- lysine (K)-specific demethylase 2Bb
- Symbol
- kdm2bb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable histone demethylase activity and transcription coregulator activity. Acts upstream of or within embryonic cranial skeleton morphogenesis; hematopoietic progenitor cell differentiation; and rRNA transcription. Predicted to be located in nucleus. Is expressed in central nervous system and retinal photoreceptor layer. Orthologous to human KDM2B (lysine demethylase 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7154787 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001810 | F-box domain |
| Domain | IPR002857 | Zinc finger, CXXC-type |
| Domain | IPR003347 | JmjC domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR041070 | Jumonji, helical domain |
| Domain | IPR041667 | Cupin-like domain 8 |
| Family | IPR050690 | JHDM1 Histone Demethylase |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Repeat | IPR006553 | Leucine-rich repeat, cysteine-containing subtype |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cupin-like domain 8 | F-box domain | JHDM1 Histone Demethylase | JmjC domain | Jumonji, helical domain | Leucine-rich repeat, cysteine-containing subtype | Leucine-rich repeat domain superfamily | Zinc finger, CXXC-type | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B6L0 | InterPro | 778 | |||||||||||
| UniProtKB:A0A8M9PAJ6 | InterPro | 513 | |||||||||||
| UniProtKB:A0A8M9PLZ6 | InterPro | 313 | |||||||||||
| UniProtKB:A0AB32TVL5 | InterPro | 1263 | |||||||||||
| UniProtKB:A0AB32TYW7 | InterPro | 1063 | |||||||||||
| UniProtKB:F6P9Q3 | InterPro | 1260 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kdm2bb-201
(1)
|
Ensembl | 4,722 nt | ||
| mRNA |
kdm2bb-202
(1)
|
Ensembl | 8,515 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers