Gene
arid1aa
- ID
- ZDB-GENE-080220-35
- Name
- AT-rich interaction domain 1Aa
- Symbol
- arid1aa Nomenclature History
- Previous Names
-
- fb79b07
- fb95g08
- wu:fb79b07
- wu:fb95g08
- zgc:171438
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity. Predicted to contribute to nucleosome binding activity. Predicted to be involved in positive regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin remodeling. Predicted to be located in nucleus. Predicted to be part of SWI/SNF complex and nBAF complex. Predicted to be active in nucleoplasm. Is expressed in hindbrain and neurons. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 2; breast cancer; carcinoma (multiple); gastrointestinal system cancer (multiple); and neuroblastoma. Orthologous to human ARID1A (AT-rich interaction domain 1A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144643 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Coffin-Siris syndrome 2 | Alliance | Coffin-Siris syndrome 2 | 614607 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001606 | ARID DNA-binding domain |
| Domain | IPR030094 | AT-rich interactive domain-containing protein 1A, ARID/BRIGHT DNA binding domain |
| Domain | IPR033388 | SWI/SNF-like complex subunit BAF250, C-terminal |
| Family | IPR021906 | SWI/SNF-like complex subunit BAF250/Osa |
| Homologous_superfamily | IPR036431 | ARID DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | ARID DNA-binding domain | ARID DNA-binding domain superfamily | AT-rich interactive domain-containing protein 1A, ARID/BRIGHT DNA binding domain | SWI/SNF-like complex subunit BAF250, C-terminal | SWI/SNF-like complex subunit BAF250/Osa |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PN46
|
2283 | |||||
|
UniProtKB:A0A8M9PDQ2
|
2285 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arid1aa-201
(1)
|
Ensembl | 8,160 nt | ||
| mRNA |
arid1aa-202
(1)
|
Ensembl | 6,858 nt |
Interactions and Pathways
No data available
Plasmids
No data available