ZFIN ID: ZDB-GENE-080220-32
Gene Name: ceramide synthase 3b
Gene Symbol: cers3b
Sequence Ontology ID : SO:0000704

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Previous Names: cers3, zgc:171494

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have sphingosine N-acyltransferase activity; predicted to be involved in ceramide biosynthetic process; predicted to localize to the endoplasmic reticulum; orthologous to human CERS3  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36568 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cers3b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal recessive congenital ichthyosis 9 Ichthyosis, congenital, autosomal recessive 9 615023
    DISEASE ASSOCIATED WITH cers3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ceramide biosynthetic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function DNA binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR006634 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR016439 (1)
  • PROSITE:PS50071 (1)
  • PROSITE:PS50922 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF03798 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cers3b-201 (1) 1598
    aberrant processed transcript cers3b-202 (1) 1108
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cers3b No data available
    MARKER RELATIONSHIPS
    cers3bContained in: [BAC] CH73-86N2 (1) (order this)
    cers3bEncodes: [cDNA] MGC:171494 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001114931 (1) 1626bp
    Genomic GenBank:CU855696 (1) 76884bp
    Select Tool
    Polypeptide UniProtKB:A8WFT1 (1) 351aa
    Sequence Clusters UniGene:119058 (1)
    Sequence Information (all 20)
    OTHER cers3b GENE PAGES
  • Alliance (1)
  • Gene:100141367 (1)
  • VEGA:OTTDARG00000032419 (1)
  • Ensembl(GRCz11):ENSDARG00000036337 (2)
  • ORTHOLOGY for cers3b (Chr: 18)
    CITATIONS (20)