Gene

fbxo6.3

ID

ZDB-GENE-080218-15

Name

F-box protein 6, tandem duplicate 3

Symbol

fbxo6.3 Nomenclature History

Previous Names

fbxo44.6
si:rp71-1k13.8
zgc:173570

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; glycoprotein catabolic process; and ubiquitin-dependent ERAD pathway. Predicted to localize to SCF ubiquitin ligase complex and cytoplasm.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fbxo6.3 Human Ortholog

No data available

Associated With fbxo6.3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001810	F-box domain
Domain	IPR007397	F-box associated (FBA) domain
Family	IPR039752	F-box only protein
Homologous_superfamily	IPR008979	Galactose-binding-like domain superfamily
Homologous_superfamily	IPR036047	F-box-like domain superfamily

Domain Details Per Protein

Protein	Length	F-box associated (FBA) domain	F-box domain	F-box-like domain superfamily	F-box only protein	Galactose-binding-like domain superfamily
UniProtKB:A0A8M6YVW7 InterPro	252
UniProtKB:A8KBJ9 InterPro	282
UniProtKB:A0A8M6Z3T2 InterPro	167
UniProtKB:A0A8M6YVA4 InterPro	197

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	zgc:173570-201 (1) Ensembl	Ensembl		1,616 nt	Select Tool ZFIN BLAST
mRNA	zgc:173570-202 (1) Ensembl	Ensembl		168 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl
Note: This gene is in a cluster of ten fbxo6/fbxo44 genes and relationships are difficult to discern. Current analysis (January 2021) suggests three fbxo44 and fbxo6 gene pairs followed by four additional fbxo44 genes.

Citations